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También en raras ocasiones se ha reportado un aumento en el tiempo de sangrado y en el tiempo de protrombina (ver Interacciones Medicamentosas) Efectos sobre el SNC: en muy raras ocasiones se han visto efectos sobre el SNC.

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Simbrinza is a combination of Brinzolamide (a carbonic anhydrase inhibitor) and Brimonidine (an alpha agonist).

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