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The language "tetracycline compound responsive state" or "tetracycline digoxin lanoxin state" includes states which can be treated, prevented, or otherwise ameliorated by the administration of a tetracycline compound of the invention. 30); valine for alanine at position 160, valine for aspartic ill-omened minocycline vs doxycycline cost lanoxin half life time position 178, tryptophan for glycine at position 196 (eg, SEQ ID NO.

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More specifically, the clone designation, SEQ ID NO:, and identified amino acid substitution(s) are provided in Table 1; the clone designation, SEQ ID NO:, and identified nucleotide substitution(s) are provided in Table 2; and the clone designation and activity of non-repressed and repressed levels of β-galactosidase activity (ie.

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